Coenzyme Q10 (CoQ-10) is often called the body’s spark plug – a vital nutrient that powers every cell and organ, from the heart to the reproductive system. As a potent antioxidant and energy cofactor, CoQ-10 supports cellular energy, fertility, and cardiovascular vitality.
However, levels naturally decline with age and certain medications, particularly statins, which can reduce CoQ-10 synthesis by up to 40%. This is why supplementing with a highly bioavailable form – like ZeroHarm CoQ-10, formulated with liposomal nanotechnology and enriched with grape seed and piperine extracts – can make a profound difference.
What Is CoQ-10 and Why Does It Matter?
CoQ-10 (also known as ubiquinone) is a fat-soluble antioxidant found in the mitochondria – the energy factories of our cells. It plays a crucial role in ATP production, which fuels everything from heart contractions to hormone synthesis.
As we age, or when taking certain medications, our CoQ-10 levels drop, leading to fatigue, reduced fertility, and cardiovascular strain.
A 2018 review in Frontiers in Physiology confirmed that CoQ-10 depletion is associated with oxidative stress, poor mitochondrial function, and increased cardiovascular risk.
https://pubmed.ncbi.nlm.nih.gov/30327549/
Fertility Benefits of CoQ-10
CoQ-10’s antioxidant and mitochondrial-supporting properties make it one of the most exciting nutrients in reproductive health research. Both male and female fertility rely heavily on healthy mitochondrial energy and protection from oxidative stress.
1. CoQ-10 and Female Fertility
As women age, the quality of their eggs (oocytes) declines largely due to mitochondrial inefficiency and oxidative damage. CoQ-10 helps counter this by restoring mitochondrial function in ovarian cells.
A 2018 study in The Journal of Assisted Reproduction and Genetics found that CoQ-10 supplementation improved ovarian response and egg quality in women undergoing IVF, particularly those with diminished ovarian reserve.
https://pubmed.ncbi.nlm.nih.gov/29238949/
Another trial published in Fertility and Sterility reported that CoQ-10 may improve fertilisation rates and embryo quality in older women, likely due to its energy-enhancing role in oocyte maturation.
https://pubmed.ncbi.nlm.nih.gov/26781281/
Key benefit: Supports egg quality, ovarian energy, and reproductive longevity.
2. CoQ-10 and Male Fertility
Male fertility is equally influenced by oxidative stress, which can impair sperm motility and DNA integrity. CoQ-10 has been shown to increase sperm count, motility, and antioxidant capacity in seminal fluid.
In a double-blind, placebo-controlled trial published in Andrologia, daily CoQ-10 supplementation for 6 months significantly improved sperm motility and morphology in men with unexplained infertility.
https://pubmed.ncbi.nlm.nih.gov/20459368/
A meta-analysis in Reproductive Biology and Endocrinology (2018) further confirmed that CoQ-10 enhances overall sperm parameters and reduces oxidative markers in semen.
https://rbej.biomedcentral.com/articles/10.1186/s12958-018-0448-8
Key benefit: Protects sperm from oxidative damage and enhances motility for improved fertility outcomes.
CoQ-10, Statins and Heart Health
Statin medications (commonly prescribed for high cholesterol) work by inhibiting the enzyme HMG-CoA reductase, which not only reduces cholesterol synthesis but also blocks CoQ-10 production – since both share the same biochemical pathway.
This can result in muscle fatigue, weakness, and reduced mitochondrial energy, particularly in the heart.
A 2018 review in Drug Design, Development and Therapy concluded that CoQ-10 supplementation improves statin-related muscle symptoms and restores mitochondrial energy metabolism.
https://pubmed.ncbi.nlm.nih.gov/30323664/
Another study in the European Heart Journal showed that CoQ-10 helps improve endothelial function and reduce oxidative stress in people with elevated cholesterol levels.
https://pubmed.ncbi.nlm.nih.gov/20605974/
Key benefit: Replenishes CoQ-10 levels depleted by statins, supporting cardiovascular vitality and energy.
Additional Antioxidant Synergy in ZeroHarm CoQ-10
Grape Seed Extract (240 mg)
Rich in oligomeric proanthocyanidins (OPCs), grape seed extract amplifies CoQ-10’s antioxidant defence. It improves circulation and endothelial health, helping oxygen and nutrients reach the heart and reproductive organs.
A 2019 clinical study in Nutrients found grape seed extract significantly reduced oxidative stress markers and improved vascular elasticity.
https://pubmed.ncbi.nlm.nih.gov/31557831/
Benefit: Enhances blood flow and antioxidant protection.
Piperine Extract (10 mg)
Piperine, from black pepper, enhances nutrient absorption by slowing intestinal transit and improving cell permeability.
A study in Planta Medica found piperine increased CoQ-10 bioavailability by up to 30%, ensuring more efficient uptake.
https://pubmed.ncbi.nlm.nih.gov/9619120/
Benefit: Maximises CoQ-10 absorption and utilisation throughout the body.
Liposomal Nanotechnology: The ZeroHarm Advantage
CoQ-10 is naturally fat-soluble and poorly absorbed in traditional forms. ZeroHarm’s liposomal nanotechnology encapsulates CoQ-10 and its co-nutrients in microscopic phospholipid spheres that mimic cell membranes, allowing the nutrients to enter the bloodstream intact and efficiently.
A 2019 study in Nanomedicine: Nanotechnology, Biology and Medicine found liposomal formulations can enhance bioavailability by up to 5-fold compared to standard capsules.
https://pubmed.ncbi.nlm.nih.gov/30948300/
Combined with freeze-drying technology, ZeroHarm preserves nutrient potency without heat or oxidation.
Frequently Asked Questions About CoQ-10
1. Can CoQ-10 improve fertility naturally?
Yes, multiple studies show CoQ-10 supports egg and sperm quality by improving mitochondrial energy and reducing oxidative stress.
2. How long does it take to see results?
For fertility and energy benefits, most studies report improvements after 8–12 weeks of consistent use.
3. Should people taking statins use CoQ-10?
Yes, statins reduce natural CoQ-10 synthesis. Supplementation can help restore energy and reduce muscle fatigue.
4. Is it suitable for vegans?
ZeroHarm CoQ-10 is naturally fermented, plant-derived, and encapsulated using vegan liposomal technology.
5. Can I take it with other supplements?
Yes. It combines well with magnesium, omega-3, or B vitamins for enhanced energy and cardiovascular support.
